Author name: Morgan Tuttle

Cure SMA has awarded a $75,000 research grant Stephen J. Kolb at Ohio State University, for his project, “Arrested Development or Neurodegeneration? An approach to understand developmental motor neuron pathology in SMA”. Dr. Kolb and his team will create a large animal model of newborn infants with SMA. They will use this model to understand […]

Cure SMA has awarded a $75,000 research grant to Chris Lorson, PhD, at the University of Missouri, for his project, “Examining the role of astrocytes and the influence upon lower motor neuron susceptibility in SMA.” SMA is caused by a mutations in the SMN1 gene. This gene is expressed in every cell in the body;

Cure SMA has awarded a $140,000 research grant to Christine DiDonato, PhD, Ann & Robert H. Lurie Children’s Hospital of Chicago, for her project, “Skeletal muscle activators as potential modulators of muscular weakness in SMA.” In SMA, the ability of the muscle to contract is impacted. This proposal focuses on skeletal muscle proteins and their

Cure SMA has awarded a $75,000 research grant to Jean Giacomotto, PhD, at the University of Queensland, for his project, “Zebrafish models of Spinal Muscular Atrophy optimized for chemical genetics and drug discovery. From proof-of-principle to new insights and treatments”. In SMA, the lack of additional “druggable” targets, beyond SMN, creates a gap in the